A Practical Guide To The Monitoring And Management Of The Complications Of Systemic Corticosteroid Therapy
Systemic corticosteroids play an integral role in the management of many inflammatory and immunologic conditions, but these agents are also associated with serious risks. Osteoporosis, adrenal suppression, hyperglycemia, dyslipidemia, cardiovascular disease, Cushing's syndrome, psychiatric disturbances and immunosuppression are among the more serious side effects noted with systemic corticosteroid therapy, particularly when used at high doses for prolonged periods. This comprehensive article reviews these adverse events and provides practical recommendations for their prevention and management based on both current literature and the clinical experience of the authors. Proceeds from the sale of this book go to the support of an elderly disabled person.
There has been substantial growth in the use of data monitoring committees in recent years, by both government agencies and the pharmaceutical industry. This growth has been brought about by increasing recognition of the value of such committees in safeguarding trial participants as well as protecting trial integrity and the validity of conclusions. This very timely book describes the operation of data monitoring committees, and provides an authoritative guide to their establishment, purpose and responsibilities.<br> * Provides a practical overview of data monitoring in clinical trials.<br> * Describes the purpose, responsibilities and operation of data monitoring committees.<br> * Provides directly applicable advice for those managing and conducting clinical trials, and those serving on data monitoring committees.<br> * Gives insight into clinical data monitoring to those sitting on regulatory and ethical committees.<br> * Discusses issues pertinent to those working in clinical trials in both the US and Europe.<br> The practical guidance provided by this book will be of use to professionals working in and/or managing clinical trials, in academic, government and industry settings, particularly medical statisticians, clinicians, trial co-ordinators, and those working in regulatory affairs and bioethics.
Transboundary Water Resources In The Balkans: Proceedings Of The Nato Advanced Research Workshop On Transboundary Water Resources In The Balkans: Initiating Regional Monitoring Networks, Held In Thessaloniki, Greece, 11-15 October 1999
A source of up-to-date information on current water resources, their quality and quantity, in every country in the Balkans. Institutional structures, water management issues and water monitoring problems are analyzed, with special reference to international waters, using characteristic case studies, including the Sava River, Lake Ohrid, The Nestos/Mesta River, the Neretva River estuary, and coastal waters in Turkey. Contributions written by experts from France, the UK and the USA demonstrate state-of-the-art electronic networking and the management of distributed water databases.
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